FIGURE 6.

The nucleotide preference for the tobacco editing apparatus at important positions around the editing site. The editing percentages of RNA substrates with 1 nt mutated to each of the 3 nt at each important position were calculated relative to the nucleotide present in wild-type substrates containing tobacco sequences. The amount of editing in mutant substrates was then compared through generation of a sequence logo using the Weblogo program (Crooks et al. 2004). The size of the characters is based on the relative editing of each substrate. Larger characters represent nucleotides that are preferred at positions around the editing site for more efficient editing.