Table 3.
Inhibition and binding constants of peptides
Peptide sequence | Docking energy (kcal/mol) | Ki I(nhibition constant) | KD (Binding constant) |
GEKD | -149 | 50 μM | 155 μM |
GERD | -115 | 40 μM | - |
SERG | -114 | 20 μM | 60 μM |
DDDD | 22 | > 100 μM | - |
The Ki values were derived from the Dixon plot. The KD values were determined from the Scatchard plot.