Table 3.

Cytokine distribution in the Gabonese population: median TNF, IFN-γ and IL-10 levels per clinical group.

	EC (min-max)	AI (min-max)	UM (min-max)	SM (min-max)	CM (min-max)
TNF (pg/ml)	41 (8–94)	36 (0–395)	8 (0–440)	175 (1–442)	209 (0–1520)
IFN-γ (pg/ml)	3,2 (0–8)	9,5 (0–31)	5 (0–395)	4 (0–201)	6,2 (2,5–9)
IL-10 (pg/ml)	14 (0–83)	102 (0–317)	134 (0–1380)	339 (0–5200)	95 (0–2300)

EC – endemic control, AI – asymptomatic infected, UM – uncomplicated malaria, SM – severe malaria (non-cerebral), CM – cerebral malaria.

Comparing group by group with the Endemic control: TNF was significantly lower in UM (p = 0,0006); IFN-γ was significantly higher in AI and CM (p = 0,02 and p = 0,007, respectively); IL-10 was significantly higher in UM (p = 0,0009), SM (p = 0,0001) and CM (p = 0,0001)