Skip to main content
. 2005 Mar;114(3):369–374. doi: 10.1111/j.1365-2567.2004.02087.x

Figure 2.

Figure 2

LAG-3 inhibits CD1a or CD14 surface expression during monocyte to DC or to macrophage differentiation. Monocytes were cultured with GM-CSF and IL-4 (a)or GM-CSF(b)and with 1 μg/ml of either hIgG1, MHC class II-specific mAb or sLAG-3. At the indicated times cells were removed and the surface expression of CD1a (a) or CD14 (b) was assessed by FACS analysis. Dot blots show the phenotype of cells of a representative experiment at day 2 and day 4. Percentage of CD1a-positive (a,b) or CD14-positive (b) cells is indicated.