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. 2000 Aug 31;2(6):489–503. doi: 10.1186/ar131

Table 3.

Deposition of IgG and complement factor C3c in knee joints of mice at various times after induction of immune-complex- mediated arthritis

IgG C3c


Mouse strain 6 h 24 h 24 h
FcRγ-/- 128 ± 6 139 ± 4 152 ± 9
C57Bl/6 (control) 126 ± 4 140 ± 9 155 ± 7

IgG and C3c were studied immunohistochemically. Deposition was assessed using an image analyser to measure the mean amount of blue light, as a measure of staining intensity, passing through a defined area in the tissue. Data are means ± SD for six mice. Significance was evaluated using Student's t test.