Figure 2.

Percentages of interleukin (IL)-12/IL-23^−/− and C57BL/6 dendritic cells (DCs) recovered after lipopolysaccharide (LPS)-induced maturation in the presence or absence of recombinant IL-12 (rIL-12). Bone marrow-derived DCs (10⁶) were cultured with LPS (1 µg/ml) or with LPS + rIL-12 (2·5 ng/ml) for 18 hr. The experiments were repeated twice, with the same pattern of results obtained on each occasion. Data represent the mean value ± standard deviation (SD) of a representative experiment. Standard deviation values were calculated from triplicate samples. *P < 0·05 versus C57BL/6 mature DCs (mDCs). **P < 0·05 versus treatment with LPS.