Figure 5.
Transfer of regulatory cells both at the day of immunization or challenge can suppress CS. Regulatory cells isolated from TNP-Ig patched mice were transferred into syngeneic mice at the day of TNP-Cl immunization (day 0) or at the day of challenge (day 4) (groups C and D). There were two additional groups: positive control (mice actively immunized with TNP-Cl) (group A) and a group of mice that were patched with TNP-Ig and then actively sensitized with TNP-Cl (suppression control) (group B). Statistical significance: group B versus group A; P < 0·001; group C versus group A; P < 0·05 and group D versus group A; P < 0·01.