Figure 1.

In vivo treatment with OX40–immunoglobulin (Ig) significantly enhanced worm expulsion from the gut. Trichinella spiralis-infected mice were treated with either OX40 or OX40 ligand (OX40L)–Ig fusion protein. Mice were killed at 7 and 14 days post infection and adult worms within the small intestine were counted. *, Significantly different from uninfected mice; †, significantly different from infected untreated mice (P < 0·05). Data are presented as the mean gut burden + the standard error of the mean for five mice per group. Results shown are representative of two independent experiments.