Table 1.
Results of vaginal cultures in mice infected with Chlamydia trachomatis mouse pneumonitis (MoPn)
| Mice (%) with positive vaginal cultures, and median (range) no. of C. trachomatis MoPn IFU (×103) per mouse per week | ||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Week 1 | Week 2 | Week 3 | Week 4 | Week 5 | ||||||||
| Mice | No. of mice/group | IFU | % | IFU | % | IFU | % | IFU | % | IFU | ||
| MMP-7 WT | 23 | 82·6 | 1·6 (0–110·6) | 65·2 | 0·4 (0–74·3) | 17·4 | 0 (0–2·7) | 0 | 0 (0) | 0 | 0 (0) | 19 (82·6) |
| MMP-7 KO | 23 | 91·3 | 3·2 (0–367·3) | 65·2 | 0·3 (0–43·9) | 39·1 | 0 (0–16·9) | 0 | 0 (0) | 13·0 | 0 (0–5·8) | 21 (91·3) |
IFU, inclusion-forming units; KO, knockout; MMP, matrix metalloproteinase; WT, wild type.