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. 2006 Feb;117(2):156–166. doi: 10.1111/j.1365-2567.2005.02274.x

Table 2.

Down-regulated transcripts in monocyte-derived dendritic cells (MoDCs) and MUTZ-3 dendritic cells (MUTZ-3-DCs) in response to inflammatory stimulation

MoDCs MUTZ-3-DCs


GenBank no. Description 0–8 hr 0–48 hr 0–8 hr 0–48 hr
Cell adhesion
NM_004357 CD151 −2·2 −2·2 −1·8 −2·5
BC005254 CLECSF2 −12·9 −16·0 −1·9 −5·4
NM_014880 DCL-1 −5·8 −8·1 −2·2 −2·7
NM_000118 ENG −3·2 −1·2 −1·1 −2·2
Cell shape
NM_001431 EPB41L2 −1·5 −2·6 1·1 −2·2
T62571 MAP7 −54·6 −90·7 −1·2 −2·3
Immune/inflammatory response
BF213829 AIF1 −2·1 −206·4 −1·3 −3·4
AA995910 ALOX5 −4·3 −5·6 −1·8 −2·0
NM_000700 ANXA1 −2·6 −4·8 −1·5 −2·1
L04636 C1QBP −2·0 −2·4 −1·4 −2·1
U62027 C3AR1 −26·6 −26·7 −1·1 −9·6
NM_002984 CCL4 3·2 −7·8 2·9 −2·1
AI421071 CCR1 −42·0 −39·7 −2·9 −1·5
NM_000397 CYBB −2·5 −2·9 1·2 −3·6
M31933 FCGR2B −10·6 −202·1 1·4 −6·0
AF198052 FYB −14·9 −8·5 −3·1 −2·9
AF208043 IFI16 −30·2 −13·8 −2·2 −2·2
AF109683 LAIR1 −1·3 −3·0 −1·4 −3·5
AF000425 LST1 −2·8 −7·8 −1·5 −2·0
Regulation of transcription
NM_004364 CEBPA −9·1 −5·0 −2·2 −1·3
AF109161 CITED2 −8·1 −20·3 −1·1 −2·5
NM_002131 HMGA1 −6·1 −5·2 −1·1 −2·2
N22468 MEF2C −12·8 −15·0 −1·7 −8·2
NM_002432 MNDA −29·3 −10·4 −4·0 −4·5
AW592266 MYBL1 −6·8 −30·2 −1·9 −2·0
U85430 NFATC3 −10·0 −2·8 −1·8 −2·2
L13974 NFE2 −129·2 −96·0 −4·3 −7·9
Signalling
NM_000677 ADORA3 −15·8 −15·7 −2·3 −2·2
NM_001666 ARHGAP4 −3·2 −17·9 −1·4 −2·3
NM_019555 ARHGEF3 −22·5 −4·8 −2·0 −2·1
NM_024701 ASB13 −1·9 −5·5 −2·5 −1·5
NM_001772 CD33 −86·0 −242·1 −1·7 −2·2
L07555 CD69 −1·7 −8·7 1·0 −2·4
NM_002183 IL-3RA 1·3 −4·8 1·8 −5·7
NM_013416 NCF4 −4·7 −5·7 −1·4 −2·9
AW574504 PECAM1 −9·3 −7·2 −2·3 −3·1
NM_002953 RPS6KA1 −4·0 1·6 −1·8 −2·2

The fold change in expression level compared with the unstimulated control sample is shown and the transcripts are grouped according to their function based on information from the Gene OntologyTM (GO) Consortium (http://geneontology.org/.)