Figure 8.
Commensal bacteria stimulate interleukin (IL)-10 and tumour necrosis factor (TNF)-α secretion by myeloid dendritic cells (DCs). DCs isolated from peripheral blood mononuclear cells (PBMCs) of healthy volunteers (n = 3) were exposed to Bifidobacterium infantis or Lactobacillus salivarius for 48 hr, and IL-10 and TNF-α levels were determined. B. infantis and L. salivarius stimulated IL-10 and TNF-α secretion (*P < 0·05 relative to untreated PBMC-derived DCs). The data are expressed as mean pg/ml ± standard error of three independent experiments.