Table 1.
The genes induced by IL-5. The values show the average of gene expression changes (log2) from the three independent experiments. The 178 prove sets (the mean fold induction is > two-fold) are shown.
| Gene symbol | Affymetrix ID | IL-4 | IL-5 |
|---|---|---|---|
| Apoptosis/Antiapoptosis | |||
| Bnip3** | 1422470_at | 1·7 | 2·3 |
| Bnip3l** | 1416923_a_at | 0·7 | 1·0 |
| Bnip3l* | 1448525_a_at | 0·9 | 1·1 |
| Cell cycle | |||
| 2600016F06Rik** | 1434745_at | 0·0 | 1·2 |
| Ccnd2* | 1416123_at | 0·4 | 1·7 |
| Ccnd2** | 1416124_at | −0·1 | 1·1 |
| Ccnd2** | 1430127_a_at | 0·3 | 1·4 |
| Ccnd2** | 1448229_s_at | 0·1 | 1·5 |
| Ccnd2** | 1455956_x_at | 0·1 | 1·3 |
| Ccne1** | 1416492_at | 0·7 | 1·0 |
| Gadd45g** | 1453851_a_at | 5·1 | 1·2 |
| Mkrn3** | 1448612_at | −0·1 | 1·5 |
| Slfnl* | 1418612_at | 2·2 | 3·3 |
| Class switch recombination | |||
| Aicda** | 1420577_at | 0·1 | 1·6 |
| Cytokine and receptor | |||
| Ccl22** | 1417925_at | −0·4 | 2·0 |
| Csf2rb1** | 1450200_s_at | −0·4 | 1·8 |
| Csf2rb1** | 1421326_at | −0·2 | 2·4 |
| Csf2rb2** | 1449360_at | −0·6 | 2·9 |
| Il1r2** | 1419532_at | −0·8 | 1·4 |
| Il2ra** | 1420691_at | −0·5 | 2·2 |
| Il2ra** | 1420692_at | −0·9 | 2·5 |
| Lta** | 1420353_at | −1·3 | 1·2 |
| Sdf2l1 | 1418206_at | 0·3 | 1·0 |
| Sema4a** | 1448110_at | 2·4 | 2·2 |
| Thy1** | 1423135_at | 2·5 | 1·7 |
| Immunoglobulin | |||
| Igh-4** | 1425247_a_at | 3·4 | 2·2 |
| Igh-4** | 1425324_x_at | 4·8 | 3·0 |
| Igh-4** | 1427756_x_at | 3·3 | 2·2 |
| Igh-4** | 1427870_x_at | 1·9 | 1·5 |
| Igj** | 1424305_at | −1·8 | 2·4 |
| Metabolism | |||
| Aldo1* | 1416921_x_at | 0·6 | 1·2 |
| Aldo1* | 1433604_x_at | 0·7 | 1·4 |
| Aldo1* | 1434799_x_at | 0·8 | 1·4 |
| Aldo1 | 1439375_x_at | 0·5 | 1·1 |
| Aldo3** | 1451461_a_at | 1·6 | 1·6 |
| Chst12* | 1448477_at | −0·1 | 1·3 |
| Glk* | 1417177_at | 0·6 | 1·1 |
| Gstt2** | 1417883_at | 0·7 | 1·0 |
| Pfkl | 1439148_a_at | 0·8 | 1·3 |
| Pfkp** | 1416069_at | 1·0 | 1·2 |
| Pfkp* | 1430634_a_at | 1·0 | 1·3 |
| Pk3** | 1417308_at | 0·6 | 1·3 |
| Psat** | 1451064_a_at | 0·3 | 1·2 |
| Psat** | 1454607_s_at | 0·3 | 1·3 |
| Pycr1** | 1424556_at | 1·3 | 2·4 |
| Scd2** | 1415823_at | 2·0 | 1·7 |
| Scd2** | 1415822_at | 1·7 | 1·5 |
| Scd2** | 1415824_at | 2·0 | 1·5 |
| Tpi* | 1415918_a_at | 0·9 | 1·6 |
| Tpi* | 1435659_a_at | 1·1 | 1·8 |
| Tpi** | 1452927_x_at | 0·9 | 1·6 |
| Ak4** | 1450387_s_at | 1·4 | 1·9 |
| Armet** | 1428112_at | 0·6 | 1·1 |
| Asns** | 1433966_x_at | 0·9 | 2·6 |
| Asns** | 1451095_at | 0·6 | 1·6 |
| Ass1** | 1416239_at | 2·4 | 1·9 |
| Miscellaneous | |||
| Anxa2** | 1419091_a_at | −0·1 | 1·1 |
| Anxa6 | 1429246_a_at | −0·2 | 1·1 |
| Crip** | 1416326_at | −0·5 | 1·5 |
| Crisp1** | 1416325_at | 0·0 | 2·9 |
| Eaf2** | 1422120_at | 0·3 | 1·2 |
| Egln1** | 1423785_at | 1·0 | 1·2 |
| Egln1 | 1451110_at | 1·2 | 1·4 |
| Egln3** | 1418649_at | 0·6 | 1·2 |
| Endog** | 1421097_at | 1·3 | 2·5 |
| Ero1l* | 1419030_at | 0·7 | 1·2 |
| Ero1l** | 1419029_at | 0·8 | 1·6 |
| Gbp2* | 1418240_at | 0·8 | 1·7 |
| Gbp2 | 1435906_x_at | 0·8 | 1·6 |
| Gbp4** | 1418392_a_at | 0·0 | 1·0 |
| Gcat** | 1417823_at | 3·6 | 4·1 |
| Glipr2** | 1428492_at | 2·2 | 1·3 |
| Gpam** | 1438040_a_at | 0·1 | 1·0 |
| Hbb-b2** | 1417184_s_at | −0·1 | 4·5 |
| Hig1 | 1416480_a_at | 0·8 | 1·1 |
| Hmmr** | 1450157_a_at | 0·6 | 1·0 |
| Ifi30** | 1422476_at | 2·0 | 1·6 |
| Klhdc2** | 1435086_s_at | 4·3 | 1·8 |
| Klhdc2** | 1460678_at | 4·5 | 2·1 |
| Lfng* | 1420643_at | 0·8 | 1·1 |
| Lmo7** | 1455056_at | 1·7 | 3·0 |
| mrg1** | 1452207_at | 1·6 | 1·6 |
| Mtdh* | 1434882_at | 1·0 | 1·3 |
| Mtdh* | 1455129_at | 1·1 | 1·1 |
| Myadm** | 1423321_at | 0·8 | 2·2 |
| Myadm** | 1439389_s_at | 1·0 | 2·0 |
| P4ha1** | 1452094_at | 0·7 | 1·2 |
| Pcp4** | 1460214_at | −0·8 | 3·5 |
| Pdcd2** | 1423534_at | 0·2 | 1·2 |
| Pdlim1** | 1416554_at | 1·1 | 1·5 |
| Prdx4 | 1416167_at | 0·1 | 1·0 |
| Rbpms** | 1425652_s_at | −0·7 | 1·0 |
| Rpn1* | 1448353_x_at | 0·5 | 1·1 |
| Scel** | 1422837_at | −0·4 | 2·4 |
| Spcs2 | 1423215_at | 0·0 | 1·0 |
| Spi2-1 | 1424923_at | 3·0 | 1·6 |
| St7** | 1418967_a_at | 4·5 | 2·0 |
| Txndc7** | 1423648_at | 0·6 | 1·0 |
| uchl3** | 1449855_s_at | 0·4 | 1·3 |
| Uck3** | 1448604_at | 0·3 | 1·1 |
| Upb1** | 1460244_at | 0·1 | 1·4 |
| Zdhhc2** | 1452654_at | 0·1 | 1·1 |
| Signalling | |||
| Cish** | 1448724_at | 3·2 | 2·0 |
| Cish2** | 1449109_at | 3·8 | 4·3 |
| Eps8* | 1422824_s_at | 0·4 | 1·1 |
| Ndr1** | 1450976_at | 1·5 | 1·9 |
| Ndr1** | 1456174_x_at | 1·0 | 1·4 |
| Ndrl** | 1420760_s_at | 1·0 | 1·2 |
| Nek2** | 1417299_at | 0·4 | 1·8 |
| Pim1** | 1423006_at | 0·9 | 1·3 |
| Pim1** | 1435872_at | 1·1 | 1·5 |
| Pkib** | 1421137_a_at | 3·1 | 1·7 |
| Pkib** | 1421138_a_at | 3·2 | 1·4 |
| Rap1ga1** | 1428443_a_at | 0·9 | 1·8 |
| Rras2** | 1417398_at | 0·0 | 1·3 |
| S100a4** | 1424542_at | 0·1 | 1·1 |
| S100a6** | 1421375_a_at | 2·5 | 5·3 |
| SSI-1** | 1450446_a_at | 4·0 | 1·6 |
| Stk39** | 1419550_a_at | 0·0 | 1·7 |
| Cytoskeltal protein | |||
| Ckap4** | 1426754_x_at | 0·8 | 1·8 |
| Ckap4 | 1426755_at | 1·2 | 2·2 |
| Ckap4** | 1452181_at | 0·6 | 1·5 |
| Ckap4* | 1455019_x_at | 0·9 | 1·7 |
| Itgb7** | 1418741_at | 0·2 | 1·4 |
| Vim** | 1438118_x_at | 0·6 | 1·2 |
| Vim** | 1450641_at | 0·6 | 1·3 |
| Vim** | 1456292_a_at | 0·8 | 1·4 |
| Fgl2* | 1421854_at | 0·6 | 1·0 |
| Fgl2* | 1421855_at | −0·5 | 1·0 |
| Transcription | |||
| Cited2** | 1421267_a_at | 1·5 | 1·6 |
| Ell2** | 1450744_at | 0·8 | 1·4 |
| Nfil3** | 1418932_at | 6·9 | 2·2 |
| Prdm1** | 1420425_at | −0·3 | 1·0 |
| Rog** | 1432459_a_at | −0·4 | 1·8 |
| Sap30* | 1417719_at | 0·1 | 1·1 |
| Xbp1** | 1420011_s_at | 1·6 | 1·1 |
| Xbp1** | 1420886_a_at | 1·5 | 1·0 |
| Xbp1** | 1437223_s_at | 1·3 | 1·0 |
| Transporter/channel | |||
| Atp1b1** | 1418453_a_at | −0·1 | 2·7 |
| Atp1b1** | 1423890_x_at | −0·2 | 3·1 |
| Atp1b1** | 1439036_a_at | −0·1 | 4·8 |
| Atp1b1** | 1451152_a_at | −0·1 | 3·0 |
| I2RF5 | 1416956_at | 0·2 | 1·1 |
| MCT4** | 1449005_at | 1·9 | 2·8 |
| Slc16a3** | 1452565_x_at | 1·7 | 2·7 |
| Slc2a1** | 1426600_at | 0·8 | 1·5 |
| Slc2a1** | 1426599_a_at | 1·3 | 2·0 |
| Slc2a1** | 1434773_a_at | 1·1 | 1·9 |
| Slc39a8** | 1416832_at | 1·1 | 1·7 |
| Slc7a5** | 1418326_at | −0·1 | 1·5 |
| Translation | |||
| Eif4ebp1** | 1417562_at | 0·7 | 1·4 |
| Eif4ebp1** | 1434976_x_at | 0·5 | 1·3 |
| Unknown | |||
| 1500032D16Rik** | 1424628_a_at | 0·6 | 1·1 |
| 1810014L12Rik** | 1416376_at | 0·6 | 1·3 |
| 2310056P07Rik** | 1451385_at | 0·5 | 1·5 |
| 2410129E14Rik** | 1452679_at | −0·6 | 1·8 |
| 2610020G18Rik** | 1451149_at | 0·6 | 1·0 |
| 2810433K01Rik* | 1450496_a_at | 0·5 | 1·0 |
| 5730592L21Rik** | 1452754_at | 0·3 | 1·1 |
| 5830411E10Rik** | 1426806_at | 1·8 | 1·7 |
| 5830411E10Rik** | 1452203_at | 1·9 | 1·7 |
| 5830411E10Rik** | 1460521_a_at | 2·0 | 1·6 |
| 9630044O09Rik* | 1424823_s_at | 1·0 | 1·5 |
| 9830147J24Rik** | 1425156_at | 0·7 | 1·9 |
| AI987662** | 1435939_s_at | −2·1 | 2·9 |
| BC003855.1** | 1425469_a_at | 1·0 | 1·5 |
| BC003855.1** | 1425470_at | 1·0 | 1·9 |
| BC003855.1** | 1425471_x_at | 0·8 | 1·6 |
| BC021921** | 1451518_at | −0·2 | 1·9 |
| BG070552** | 1455279_at | 0·3 | 2·3 |
| BM241271** | 1434380_at | 1·1 | 2·8 |
| D10Ertd214e | 1416849_at | 0·6 | 1·3 |
| D130043N08Rik** | 1418507_s_at | 4·0 | 4·5 |
| D530020C15Rik** | 1423747_a_at | 1·2 | 1·6 |
| D530020C15Rik** | 1423748_at | 1·1 | 1·3 |
| E330009J07Rik** | 1449056_at | 0·4 | 1·0 |
| E430036I04Rik** | 1423614_at | 0·9 | 1·3 |
| LOC381240** | 1438932_at | 0·4 | 1·3 |
Significant differences as determined by one-way anova are represented as
*
P < 0·05
**
P < 0·01