Figure 2.
Cytokine production by peripheral blood mononuclear cells (PBMCs) from allergic and nonallergic women in response to stimulation of the innate immune system, at pregnancy and 2 years after measured by enzyme-linked immunospot assay (ELISPOT). Results are expressed as the ratio between stimulated PBMCs and unstimulated PBMCs (stimulation index). (a) Interleukin-10 (IL-10) production by unstimulated cells. (b) IL-10 production by lipopolysaccharide (LPS) (0·05 ng/ml)-stimulated cells. (c) IL-12 production by unstimulated cells. (d) IL-12 production by LPS (0·05 ng/ml)-stimulated cells. ○, outliers; *, extreme outliers. Boxes cover the middle 50% of the data values, between the 25th and 75th percentiles, the central square being the median. Lines extend out to non-outlier maximum and non-outlier minimum.