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. 2004 Jan;111(1):35–40. doi: 10.1111/j.1365-2567.2003.01768.x

Figure 1.

Figure 1

Effect of cAMP-elevating agents on IFN-γ and IL-5 production. Spleen cells from DBA/1 mice immunized with type II collagen in alum adjuvant were cultured in the presence of type II collagen (50 μg/ml) plus one of the four cAMP-elevating agents. The agents were added 30 min prior to addition of collagen and cytokines were measured by ELISA after 72 hr. Data shown are mean ± SE and the experiment is a representative of three comparable experiments, giving consistent results. P-values refer to differences between groups treated with cAMP-elevating agents and untreated controls.