Table 1.
Anti-CD40 mAb does not prime the immune response to oral OVA*
| Proliferation (counts/minute) | ||
|---|---|---|
| Antibody | PBS | OVA |
| Rat IgG | 5871 ± 1081 | 5122 ± 1078 |
| Anti-CD40 | 3919 ± 916 | 3787 ± 667 |
Mice were fed 20 mg OVA or PBS and received the indicated antibody simultaneously. Two weeks later, splenocytes were prepared and cultured in the presence of 50 μg/ml of OVA for 96 hr, including 18-hr [3H]thymidine incorporation.