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Expression of cytokine mRNA in synovial tissue from knees of IL-12 knockout mice (IL-12–/–) in comparison with their wild-type littermates (IL-12+/+), 3 d after intra-articular inoculation with 6 μg CpG ODN. Each bar represents the mean number and SEM of positive cells per mm2 in synovial tissue from four mice. NS = not significant.
