Table 4.

Effect of praziquantel treatment on the involution of granulomatous response in Schistosoma mansoni-infected mice

Months	Mean granuloma area (μm2 × 10−3 ± SEM)
after
treatment	Control	Treated
3	77.65 ± 4.34	50.75 ± 1.48**
	(6)a	(7)
6	58.54 ± 5.35	36.59 ± 2.03*
	(9)	(13)
12	ND	26.36 ± 2.38**
		(7)

The results are presented as mean ± SEM.

^aValues in parentheses are numbers of mice used.

Mice treated with praziquantel for 12 months were compared with untreated controls at 6 months.

^*Significant at the P < 0·001 level compared with controls.

^**Significant at the P < 0·0001 level compared with untreated controls at 6 months.