. 2004 Mar;111(3):318–322. doi: 10.1111/j.1365-2567.2004.01811.x

Table 1.

Comparative analysis of HLA allele frequency in historical and recently diagnosed TB patients, versus healthy controls in the Campania region of southern Italy

HLA Alleles	Recently diagnosed TB patients % (N = 68)	Historical TB patients % (N = 54)	Controls % (N = 1089)	Healthy age-matched controls^* % (N = 44)
HLA-A2	52.94	29.62	42.24	52.27
	RR = 1.49	RR = 0.6		RR = 0.38
	^†P = NS^‡	P = 0.06		P = 0.03
		^§P_c = NS		P_c = NS
HLA-A3	10.29	16.66	22.68	18.18
	RR = 0.39
	P = 0.008	P = NS		P = NS
	P_c = NS
HLA-B14	8.82	16.66	4.77	NF^¶
	RR = 1.9	RR = 3.9		P = 0.003
	P = NS	P = 0.001		P_c = NS
		P_c = NS
HLA-B50	2.94	11.11	3.67	9.09
	RR = 0.79	RR = 3.2
	P = NS	P = 0.01		P = NS
		P_c = NS
HLA-DR4	8.82	29.62	15.36	20.45
	RR = 0.6	RR = 2.7		RR = 1.6
	P = NS	P = 0.001		P = NS
		P_c = NS
HLA-DR7	10.29	29.62	23.59	27.27
	RR = 0.37	P = NS		P = NS
	P = 0.005
	P_c = NS
HLA-DR8	11.76	5.55	3.94	6.82
	RR = 3.2
	P = 0.007	P = NS		P = NS
	P_c = NS

Statistical analysis was performed by using Fisher's two tailed exact test.

^†

Not significant.

^‡

Corrected P-value (see for details).

^§

To be compared with the historical TB patients.

^¶

Not found.