. 2004 Mar;111(3):318–322. doi: 10.1111/j.1365-2567.2004.01811.x

Table 3.

Analysis of HLA antigen association in historical and recently diagnosed TB patients versus controls

HLA phenotype	Recently diagnosed TB patients % (N = 68)	Historical TB patients % (N = 54)	Controls % (N = 1089)	Healthy age-matched controls^* % (N = 44)
HLA-A2⁺,-DR4⁻	50	16·66	34·89	43·18
	RR = 1·86	RR = 0·37		RR = 0·26
	^†P = 0·009	P = 0·003		P = 0·003
	^‡P_c = NS	^§P_c = NS		P_c = NS
HLA-A2⁺,-B14⁻	51·47	20·37	39·11	52·27
	RR = 1·6	RR = 0·39		RR = 0·23
	P = 0·03	P = 0·003		P = 0·0009
	P_c = NS	P_c = NS		P_c = NS
HLA-A2⁺,-DR4⁻,B14⁻	48·52	9·25	33·33	43·18
	RR = 1·88	RR = 0·2		RR = 0·13
	P = 0·008	P = 0·00005		P = 0·0001
	P_c = NS	P_c = 0·01		P_c = 0·02
HLA-A2⁻,-DR4⁺,B14⁺	NF^¶	5·55	1·28	NF
		RR = 1·88		P = NS
	P = NS	P = 0·008
		P_c = NS
HLA-DR4⁺ and/or -B14⁺	17·64	61·11	20·75	20·45
	RR = 0·8	RR = 6		RR = 6·1
	P = NS	P = 0·000004		P = 0·00004
		P_c = 0·0008		P_c = 0·008

Statistical analysis was performed by using Fisher's two tailed exact test.

^†

Corrected P-value (see for details).

^‡

Not significant.

^§

To be compared with the historical group of TB patients.

^¶

Not found.