Figure 6.

Effect of CpG-oligonucleotide (ODN) stimulation on the survival of natural interferon-producing cells (NIPCs). SWC3⁺ cells were treated for 1 or 3 days with medium (negative control), interleukin-3 (IL-3), UV-inactivated transmissible gastroenteritis virus (UV-TGEV) positive control, or different CpG-ODNs (D32, D19, 2216 or 1585). (a) SWC3/CD4 phenotype of the cells at 1 day post-treatment and region (R1 = 1 and R2 = 2) definition. (b) Number of viable cells in R1 (SWC3^low CD4^high NIPC) at 1 and 3 days post-treatment. (c) Number of viable cells in R2 (other SWC3⁺ cells) at 1 and 3 days post-treatment.