Figure 1.
Effect of fetal exposure to bisphenol A (BPA) on production of anti-hen egg lysozyme (HEL) immunoglobulin G (IgG). Female mice were administered per os (p.o.) the indicated doses of BPA, daily over a period of 18 days, commencing on the day of pairing with males (day 0). On day 77, male littermates of 8 weeks were immunized with HEL and, 3 weeks later, anti-HEL IgG in sera was measured as described in Materials and methods. Values represent the mean ± standard error of the mean (SEM) of five mice. ELISA, enzyme-linked immunosorbent assay. *P < 0·05 versus control (0 µg/kg BPA).