Figure 2.

Immediate phase AR hypersensitivity responses. Mice (four mice/group) were sensitized and challenged as outlined in Fig. 1. (a) Fifteen min after the final i.n. OVA challenge, mice received clinical scores, as described in methods and (b) NLF samples were collected for histamine determinations. Results are reflective of three separate experiments (*P ≤ 0·05 for comparisons to OVA sensitized and challenged mice receiving no intervention).