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. 2004 Sep;113(1):121–129. doi: 10.1111/j.1365-2567.2004.01937.x

Figure 1.

Figure 1

Enhancement of long-terminal repeat (LTR) activation by lipid-associated membrane proteins (LAMPs) through nuclear factor-kappa B (NF-κB). (a) THP-1 cells were transfected with 0·1 µg/ml pHIV-LTR-luc and 0·01 µg/ml pRL-TK. The cells were stimulated with the indicated concentrations of LAMPs. All values represent the mean and standard deviation (SD) of three assays. (b) THP-1 cells were transfected with 0·1 µg/ml pHIV-LTR-luc (LTR), pHIV-LTRΔSP1-luc (ΔSP-1), pHIV-LTRΔκB-luc (ΔNFκB) or pHIV-LTRΔκBSP1-luc (ΔSP-1ΔNF-κB) in combination with 0·01 µg/ml pRL-TK. The cells were stimulated with 0·5 µg/ml Mycoplasma penetrans LAMPs and 1·0 µg/ml M. fermentans LAMPs. All values represent the mean and SD of three assays.