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. 2004 Sep;113(1):121–129. doi: 10.1111/j.1365-2567.2004.01937.x

Figure 2.

Figure 2

Enhancement of long-terminal repeat (LTR) activation through Toll-like receptor 2 (TLR2). (a) THP-1 cells were transfected with 0·1 µg/ml pHIV-LTR-luc and 0·01 µg/ml pRL-TK. The cells were treated with anti-TLR2 monoclonal antibody (mAb) followed by stimulation with 0·5 µg/ml Mycoplasma penetrans lipid-associated membrane proteins (LAMPs) and 1·0 µg/ml M. fermentans LAMPs. All values represent the mean and standard deviation (SD) of three assays. (b) 293T cells were transfected with the indicated concentrations of pFLAG-TLR2, 0·01 µg/ml pHIV-LTRΔSP1-luc, and 0·01 µg/ml pRL-TK. The cells were stimulated with 0·5 µg/ml M. penetrans LAMPs and 1·0 µg/ml M. fermentans LAMPs. All values represent the mean and SD of three assays.