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. 2004 Sep;113(1):121–129. doi: 10.1111/j.1365-2567.2004.01937.x

Figure 3.

Figure 3

Cooperation of Toll-like receptor (TLR)1, TLR6 and TLR2 for long-terminal repeat (LTR) activation by lipid-associated membrane proteins (LAMPs). 293T cells were transfected with the indicated concentrations of pFLAG-dTLR6 (a) or pFLAG-dTLR1 (b), 0·1 µg/ml pFLAG-TLR2, 0·01 µg/ml pHIV-LTRΔSP1-luc and 0·01 µg/ml pRL-TK. The cells were stimulated with 0·5 µg/ml Mycoplasma penetrans LAMPs or 1·0 µg/ml M. fermentans LAMPs. All values represent the mean and standard deviation (SD) of three assays. DN, dominant negative.