Figure 3.

The induction of T-dependent germline transcript production is affected strongly by the absence of CD154. Mice were immunized with NP-CGG and killed B. pertussis and responses assessed 3 and 7 days after immunization. Closed and open circles, respectively, represent individual lymph node responses from wild-type and CD154-deficient mice. (a) Levels of γ1 germline transcript production and (b) levels of γ2a germline transcript production. Median values for each of the groups are included above the data points. Data are representative of at least two repeat experiments.