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Effect of genetic deficiency of PARP-1 on cytosol expression of Bcl-2 and Bax in the colon. (a) Representative Western blot analysis for Bcl-2 and Bax. (b) Image analysis of Bcl-2 and Bax content determined by densitometry. Fold increase was calculated versus respective sham value (time 0) set to 1·0. *P < 0·05 versus wild-type (PARP-1+/+) mice.
