Figure 1.
Experimental metastasis of B16 melanoma cells in IFN-γ−/−, IFN-γR−/−, and wild-type mice. B16 melanoma cells (1 × 105 cells) were injected through the tail vein, and after 14 days, the lungs (a–c) and the liver (d–f) were removed, and the photographs were taken. Wild-type: a, d; IFN-γ−/−: b, e; IFN-γR−/−: c, f. Arrowheads, B16 metastatic colonies.