Figure 2.

Number of the B16 metastatic colonies on the liver and the lung in IFN-γ^−/−, IFN-γR^−/−, and wild-type mice. (a) Number of the colonies on the liver and the lungs shown in Fig. 1 was counted, and the average ±SD is shown. Results are reproducible in three independent experiments. (b) The diameter of each colony was measured on the histological sections, and the average size and SD are shown. *P < 0·05, **P < 0·01 (IFN-γ^−/− versus wild-type and IFN-γR^−/− mice).