Table 2.
Summary of anti-nuclear antibody (ANA) findings in recipients of interferon-γ (IFN-γ) gene knockout (gko) grafts
No. of mice with fluorescent nucleii | No. of mice with a homogeneous nuclear staining pattern | No. of mice with a peripheral nuclear staining pattern | Serum dilution at which nuclear staining was no longer detectable* |
---|---|---|---|
9/20 | 7/9 | 2/9 | 1 : 32 (75%) |
1 : 64 (25%) |
Pooled sera from MRL/lpr mice consistently stained nucleii of HeP-2 cells at dilutions of less than 1 : 2000.