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. 2002 Jan;105(1):1–8. doi: 10.1046/j.1365-2567.2002.01329.x

Figure 1.

Figure 1

TNF mRNA expression in the colon of a patient with active ulcerative colitis and in experimental colitis. In situ hybridizations with specific TNF antisense probes reveal the presence of TNF mRNA expressing cells (arrows) in the affected: from a patient with active ulcerative colitis (a), whereas numerous TNF mRNA expressing cells are found in the colonic mucosa adjacent to the colonic lumen (L) in a RAG2−/− mouse on day 24 post adoptive transfer of colitogenic CD4 CD45RBhi T cells (b).