Table 2. CC chemokines and chemokine receptors superfamily.
| Systematic name | Human ligand | Mouse ligand | Chemokine receptors |
|---|---|---|---|
| CC family | |||
| CCL1 | I-309 | TCA-3/P500 | CCR8 |
| CCL2 | MCP-1/MCAF | JE/MCP-1 | CCR2 |
| CCL3 | MIP-1α/LD78 | MIP-1α | CCR1; CCR5 |
| CCL4 | MIP-1β/AT744.1/LAG-1 | MIP-1β | CCR5 |
| CCL5 | RANTES | RANTES | CCR1; CCR3; CCR5 |
| CCL6 | Unknown | C10/MRP-1 | Unknown |
| CCL7 | MCP-3 | MARC/FIC | CCR1-CCR3 |
| CCL8 | MCP-2/HC14 | MCP-2 | CCR1-CCR3; CCR5 |
| CCL9/10 | Unknown | MIP-1γ/MRP-2/CCF18 | Unknown |
| CCL11 | Eotaxin | Eotaxin | CCR3; CCR5 |
| CCL12 | Unknown | MCP-5 | ?CCR2 |
| CCL13 | MCP-4/CKβ-10/NCC-1 | Unknown | CCR1-CCR3; CCR5 |
| CCL14 | HCC-1-/NCC-2 | Unknown | CCR1; CCR3; CCR5 |
| CCL15 | HCC-2/MIP-5/Lkn-1/MIP-1δ | Unknown | CCR1; CCR3; CCR5 |
| CCL16 | HCC-4/LEC/NCC-3/4 | LCC-1 | CCR8 |
| CCL17 | TARC/dendrokine | TARC | CCR4 |
| CCL18 | DC-CK1/PARC/MIP-4/AMAC-1 | Unknown | Unknown |
| CCL19 | MIP-3β/ELC/exodus-3/CKβ-11 | MIP-3β | CCR7 |
| CCL20 | MIP-3α/LARC/exodus-1 | MIP-3α | CCR6 |
| CCL21 | 6Ckine/TCA4/exodus-2/SLC | 6Ckine | CCR7 |
| CCL22 | MDC/STCP-1 | ABCD-1 | CCR4 |
| CCL23 | MPIF-1 | Unknown | CCR1 |
| CCL24 | MPIF-2/Eotaxin-2 | Unknown | CCR3 |
| CCL25 | TECK | TECK | CCR9 |
| CCL26 | Eotaxin-3 | Unknown | CCR3 |
| CCL27 | CTACK/ALP/ILC | CTACK/Eskine/ALP | CCR10 |
ABCD-1, activated B cells and dendritic cells-1; AMAC-1, alternative macrophage activation-associated CC-chemokine; CCL, CC chemokine ligand; CTACK, cutaneous T-cell-attracting chemokine; DC-CK1, dendritic-cell-derived C-C chemokine; ELC, EBI1-ligand chemokine; FIC, fibroblast-induced cytokine; HCC, haemofiltrate CC chemokine; ILC, interleukin-11 receptor α-locus chemokine; LARC, liver and activation-regulated chemokine; LCC 1, liver-specific CC chemokine 1; LEC, liver-expressed chemokine; Lkn 1, leukotactin 1; MCAF, monocyte chemotactic activating factor; MCP, monocyte chemoattractant protein; MDC, macrophage-derived chemokine; MIP, macrophage inflammatory protein; MPIF, myeloid progenitor inhibitory factor-1; MRP, multidrug resistance-associated protein; PARC, pulmonary and activation-regulated chemokine; RANTES, regulated upon activation normal T-cell expressed and secreted; TARC, thymus and activation-regulated chemokine; TCA, T-cell activation gene; TECK, thymus-expressed chemokine; SLC, secondary lymphoid tissue chemokine; STCP-1, stimulated T-cell chemotactic protein. For recent updates on the nomenclature, see the review in this issue by Watson73.