Table 1. Recently characterized human chemokines and receptors*.
Novel chemokine/receptor | Expression | Receptor or ligand | Activity |
---|---|---|---|
CXCL16 | Antigen-presenting cells:membrane bound or released | CXCR6(STRL33/Bonzo/TYMSTR) | Activated T-cell chemotaxis |
CCL28 (MEC) | Mucosal epithelium | CCR10 CCR3 | Memory T-cell and″eosinophil chemotaxis |
CCR11 | Heart, small intestine | CCL19 (ELC)CCL21 (SLC)CCL25 (TECK) | Binding only |
Seehttp://csp.medic.kumamoto-u.ac.jp/fora full listing of chemokines, receptors and their interactions.
ELC, Epstein–Barr virus-induced receptor ligand chemokine; MEC, mucosae-associated chemokine; SLC, secondary lymphoid tissue chemokine; STRL33, seven transmembrane domain receptors from lymphocytes clone 33; TECK, thymus-expressed chemokine; TYMSTR, T-lymphocyte-expressed seven-transmembrane domain receptor.