Table 1. Percentage of infants with cytotoxic responses in vaccinated groups.
Responders* | High Kill† | |
---|---|---|
≥ 5% | ≥ 10% | |
BCG-specific cytotoxicity | ||
Cords (n = 19) | 32% | 11% |
Unv 10 week (n = 9) | 67% | 56% |
DID (n = 7) | 86% | 86% |
Del DID (n = 10) | 80% | 80% |
JID (n = 8) | 100% | 100% |
JPC Big (n = 6) | 100% | 100% |
JPC Bio (n = 20) | 80% | 75% |
H37Rv-specific cytotoxicity | ||
Cords (n = 19) | 21% | 11% |
Unv 10 week (n = 7) | 29% | 14% |
DID (n = 7) | 71% | 57% |
Del DID (n = 6) | 83% | 83% |
JID (n = 6) | 83% | 67% |
JPC Big (n = 6) | 100% | 83% |
JPC Bio (n = 20) | 55% | 30% |
Responders are arbitrarily defined as ≥5% antigen-specific cytotoxicity.
Strength of killing is indicated by percentage of infants ≥ 10% antigen-specific cytotoxicity.
Data represents E:T ratio of 3:1.