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. 2002 Mar;105(3):263–266. doi: 10.1046/j.1365-2567.2002.01379.x

Table 1. Studies demonstrating association between tumour-expressed FasL and apoptosis and loss of TILs in situ in human cancers.

Tumour type Ref. Cases studied (n) FasL's association with apoptosis and loss of TILs
Ovarian 10 132 Decreased CD3+ and CD8+ TILs
Colon 13 41 Increased apoptosis of TILs (P < 0·01); decreased TIL numbers
Oesophageal 14 106 Decreased CD8+ TILs (P = 0·0011); increased apoptosis of TILs″(n = 6, P < 0·05);9 decreased TIL numbers (n = 6, P < 0·05)9
Mycosis fungoides lymphoma 12 21 Increased apoptosis of CD8+ TILs; decreased CD8+ TIL numbers (P < 0·02)
Gastric cancer 11 100 Increased apoptosis of TILs (P = 0·057)
Angiosarcoma 15 40 Decreased CD3+ and CD8+ TILs (P ≤ = 0·004)