Figure 5.
AICD of bystander CTLs induced by the tumour-activated CTLs. C3H/HeJ anti-EL4 (k anti-b) and C3H/HeJ anti-LF− (k anti-d) were mixed at a ratio of 2:1 during the preincubation. This mixture was then preincubated for 21 hr with BW, EL4, or LF− cells, and then tested for cytotoxicity in a 2-hr 51Cr-release assay on EL4 target cells at a 2·5:1 effector to target ratio.