Table 1.
Chain composition of laminin isoforms and known receptors of the integrin family
| Isoform | Subunits | Integrin receptors |
|---|---|---|
| Laminin-1 (LN-1) | α1β1γ1 | α1β1, α2β1, α6β1, α6β4, α7β1 |
| Laminin-2 (LN-2) | α2β1γ1 | α1β1, α2β1, α3β1, α6β1, α6β4, α7β1 |
| Laminin-3 (LN-3) | α1β2γ1 | ND |
| Laminin-4 (LN-4) | α2β2γ1 | presumed to be similar to those of LN-2 |
| Laminin-5 (LN-5) | α3β3γ2 | α3β1, α6β4, α6β1 |
| Laminin-6 (LN-6) | α3β1γ1 | ND |
| Laminin-7 (LN-7) | α3β2γ1 | ND |
| Laminin-8 (LN-8) | α4β1γ1 | α6β1 |
| Laminin-9 (LN-9) | α4β2γ1 | ND |
| Laminin-10 (LN-10) | α5β1γ1 | α3β1, α6β1 |
| Laminin-11 (LN-11) | α5β2γ1 | α3β1, α6β1 |
| Laminin-12 (LN-12) | α2β1γ3 | ND |
| Laminin-13 (LN-13) | α3β2γ3 | ND |
| Laminin-14 (LN-14) | α4β2γ3 | ND |
| Laminin-15 (LN-15) | α5β2γ3 | ND |
ND, not determined.