Table 1. Region showing evidence for linkage to asthma and allergic phenotypes in genome-wide screening.
| Locus | Australian4 | CSGA5,6 | Dutch7 | French8 | German9 | Japanese10 | Hutterites11 |
|---|---|---|---|---|---|---|---|
| 1p | – | Asthma (Hispanic)6 | – | Asthma | Eosinophils | – | Skin test |
| Total IgE | Asthma | ||||||
| Specific IgE | |||||||
| 2p | – | – | – | – | Asthma | – | – |
| BHR | |||||||
| Total IgE | |||||||
| RAST | |||||||
| Specific IgE | |||||||
| 2q | – | Asthma (Hispanic)5 | – | – | Total IgE | – | Skin test |
| 3p | – | – | BHR | – | – | – | Asthma |
| Skin test | |||||||
| 4q | BHR | – | – | – | RAST | Mite-sensitive atopic asthma | – |
| 5p | – | Asthma (African American)5 | – | – | Specific IgE | – | BHR |
| 5q | – | – | BHR | – | – | Mite-sensitive atopic asthma | Asthma |
| Asthma symptoms | |||||||
| 6p | Eosinophils | Asthma (Caucasian)6 | – | – | Asthma | Mite-sensitive atopic asthma | – |
| Atopy | RAST | ||||||
| Total IgE | |||||||
| Eosinophils | |||||||
| 7p | BHR | – | – | – | RAST | – | – |
| Total IgE | |||||||
| 8p | – | – | – | – | – | – | Asthma |
| 9p | – | – | – | – | BHR | – | Asthma symptoms |
| 9q | – | – | – | – | Asthma | – | – |
| 10q | – | – | Total IgE | – | Specific IgE | – | – |
| 11p | – | Asthma (Caucasian)5 | – | Total IgE | – | – | Skin test |
| 11q | Total IgE | Asthma (African ″American)6 | – | Total IgE | Eosinophils | – | – |
| Skin test | |||||||
| 12q | – | Asthma (Caucasian)5 | Total IgE | Eosinophils | – | Mite-sensitive atopic asthma | Asthma |
| Skin test | |||||||
| 13q | Atopy | Asthma (Caucasian)5 | – | Eosinophils | – | Mite-sensitive atopic asthma | Asthma symptoms |
| 14q | – | Asthma (Caucasian)5 | – | – | – | – | Asthma |
| 15q | – | – | – | – | Total IgE | – | – |
| Specific IgE | |||||||
| 16q | Total IgE | – | – | – | – | – | Skin test |
| 17p | – | Asthma (African ″American)5 | – | – | – | – | – |
| 17q | – | – | Total IgE | Asthma | – | – | – |
| Skin test | |||||||
| 18p | – | – | – | – | – | – | Asthma symptoms |
| 19q | – | Asthma (Caucasian)5 | – | – | – | – | BHR |
| 20p | – | – | – | – | – | – | Skin test |
| 21q | – | Asthma (Caucasian)5 | – | – | – | – | – |
| Xq | – | – | – | – | Total IgE | – | – |
| Eosinophils |
Only values P<0·01 are shown.