Figure 8.

Proliferation rates, as assessed by incorporation of [³H]-thymidine (counts per minute [cpm]) in: first-passage (white bars) and conventional (conv.) fourth-passage (dark gray bars) normal skin-FB (n = 3 each) (A) isolated first-passage (white bars), isolated (isolat.) fourth-passage (light gray bars), and conventional fourth-passage (dark gray bars) OA-SFB (n = 3, 3, and 4, respectively) (B) and isolated first-passage (white bars), isolated (isolat.) fourth-passage (light gray bars), and conventional fourth-passage (dark gray bars) RA-SFB (n = 4, 3, and 5, respectively) (C), at rest (control) or following stimulation with IL-1β (50, 100, or 150 U/ml) or PDGF-BB (2.5, 5, or 10 U/ml). See Results for details. @ P ≤ 0.05 for the comparison between cytokine-stimulated FB and non-stimulated control FB within the same FB preparation. *P ≤ 0.05 for the comparison between OA-SFB and RA-SFB.