Figure 1.

Interaction of antibody-opsonized foot-and-mouth disease virus (FMDV) with macrophages (Mφ). (a) [³⁵S]Methionine-labelled FMDV, opsonized with specific antibody (○) or unopsonized (•), was added to primary Mφ cultures for the times shown on the x-axis. Following washing of the cultures, the quantity of radiolabel associated with the cells was measured as described in the Materials and methods. (b) Reduction of the infectivity of FMDV, opsonized with specific antibody, was measured after association with Mφ, as described above for Fig. 1(a). The results from three experiments (±SD) are shown.