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(a–d) Splenocytes from A2.1Kb mice immunized with E7/A2/1(a), E7/A2/2 (b, d) or E7/Db (c)peptides, were restimulated in vitro with cognate peptide and reacted with unpulsed EL4.A2.E7 and EL4.A2 target cells (a–c) or EL4.A2.E7 target cells pulsed with peptide E7/A2/2 (e)as indicated, in a 4-hr 51Cr-release assay. (e) Splenocytes from A2.1Kb mice and C57BL/6 mice immunized with E7/A2/2 peptide were restimulated in vitro and reacted with CaSki cells in a 4-hr 51Cr-release assay.
