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Effect of prevaccination with TT on induction of anti-Id antibodies by patients' DNAscFv–FrC vaccines. Groups of six mice were prevaccinated with TT/alum (black columns) or alum (grey columns) at day −42. Mice were injected patient's DNAscFv–FrC vaccine at day 0, 21 and 42 and bled at days 21, 42 and 63 to measure anti-Id antibody levels. Bars indicate SEM.
