Table 1. Analysis of tumour derived V genes*.
| VH | VL | ||||||
|---|---|---|---|---|---|---|---|
| Patient | Immunoglobulin | V-gene | % homology* | JH | V-gene | % homology* | JL |
| I GH | IgGλ | V4–59 | 90·9 | JH4b | VλIII (IGLV3S6) | 89·6 | Jλ2 |
| II JC | IgAκ | V3–23 | 93·8 | JH4b | VκIII (A27) | 95·1 | Jκ2 |
| III GS | IgGκ | V3–7 | 88·8 | JH4b | VκI (012/02) | 88·9 | Jκ5 |
| IV JW | IgGκ | V2–70 | 96·6 | JH4b | VκIII (38 k/L6) | 97 | Jκ2 |
| V MW | IgGκ | V5–51 | 95·5 | JH4b | VκI (018/08) | 95·8 | Jκ2 |
| VI PR | IgGλ | V2(S12–4) | 93·3 | JH3b | VλI (1c/DPL2) | 94·7 | Jλ7 |
| VII WD | IgGκ | V2(S12–4) | 92·5 | JH5b | VκI (02/DPK9) | 90·9 | Jκ1 |
| VIII FA | IgGκ | V2(S12–7) | 86·6 | JH4b | VκIII (38 k/L6) | 95·4 | Jκ4 |
| IX PC | IgGκ | V1–3 | 88·4 | JH6b | VκI (02/DPK9) | 95·8 | Jκ3 |
*
Nucleotide sequences have been deposited in the GenBank/EMBL database: accession numbers are AF442750–67.