Mistletoe lectins (ML) enhance mucosal immunoglobulin A (IgA) responses to co-administered glycoprotein D2 (gD2) following nasotracheal immunization. Data show gD2-specific IgA antibody titres in secretions of mice immunized on days 1, 14, 35 and 49 with gD2 (5 µg) alone or gD2 (5 µg) together with cholera toxin (CT) (1 µg), MLI (1 µg), MLII (1 µg) or MLIII (1 µg). Responses were measured 2 weeks after the final immunization in (a) saliva, (b) vaginal wash, (c) nasotracheal wash and (d) intestinal wash. The diamond symbols represent antibody titres in individual animals and the symbol (–) represents the mean titre. P-values in parentheses refer to significance of data compared with the gD2-only group.