Figure 4.

Analysis of OVA-specific IgE (a) and total IgE (b) in serum from immunized but not aerosol challenged wild-type and knockout mice lacking γδ T cells (TCRγδ KO). OVA-specific IgE was measured at three different serum dilutions (1 : 3, 1 : 9 and 1 : 27). In this dilution range, the OD-values were significantly lower in OVA-immunized TCRγδ mice than in OVA-immunized wild-type mice (P < 0·01, anova). The amount of total IgE in serum samples was calculated from a standard curve with a mouse IgE isotype standard. *P < 0·05. Data are also shown for non-immunized wild-type control mice.