Figure 8.
Airway eosinophilia is diminished in B cell deficient mice. The number of eosinophils and total leukocytes in BALF was analysed 18 hr after the last of three repeated exposures of aerosolised OVA in presensitized B-cell deficient (Igh-6tm1Cgn) or wild-type C57BL/6 mice. Mean values and standard deviations are depicted. Four animals in the untreated control groups. Nine animals in the OVA challenged wild-type group and seven animals in the OVA challenged B cell deficient group. The figure represents one of three experiments with similar results. Similar results were also obtained when B-cell deficient mice on the C57BL/10 background were compared with C57BL/10 wild-type mice (data not included). **P < 0·01 versus the OVA challenged wild-type group.