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. 2003 Jan;108(1):50–54. doi: 10.1046/j.1365-2567.2003.01547.x

Figure 5.

Figure 5

PEC from IL-12 p40 knockout and wild type mice respond differently to stimulation by IL-18. Peritoneal exudate cells (PEC) from thioglycollate-treated mice were stimulated in vitro with IL-18 (10 ng/ml), supernatants were sampled at 24 and 48 hr for cytokine concentrations. Unstimulated cells did not produce detectable amounts of cytokines (not shown). (a) PEC from C57BL/6 IL-12 p40-deficient mice do not secrete IL-12. (b) PEC from C57BL/6 IL-12 p40-deficient mice secrete more TNF-α than C57BL/6 mice.