Figure 3.

Interferon-γ (IFN-γ) production in infected wild-type (WT) and inducible nitric oxide synthase-knockout (iNOS-KO) mice upon stimulation with concanavalin A (Con A) and VF-antigen in vitro. Splenocytes were collected at 4 months postinfection (p.i.). Identical results were obtained from animals at 1 month p.i. (data not shown). The figure shows results from one representative out of two independent experiments. *, † and ‡ indicate statistically significant differences, assessed upon five different measurement points per group (P < 0.05).