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. 2003 Mar;108(3):352–364. doi: 10.1046/j.1365-2567.2003.01609.x

Figure 7.

Figure 7

Long-term production of IFN-γ and IL-5 by lung explants exposed to anti-CD3 mAb. Lung explants were prepared from 14 to 116 days after i.n. delivery of BCG. After stimulation with soluble anti-CD3 mAb, the secretion of IL-5 and IFN-γ peaked, respectively, at 6 and 24 hr culture period. These intervals were used for monitoring IL-5 and IFN-γ production by the explants. From 28 to 90 days the production of IFN-γ was significantly higher in BCG-immunized than in control mice (P < 0·05)(a). There were no significant differences in the production of IL-5 among the two groups of mice(b). Results are expressed as mean ± SEM.