. 2003 Mar;108(3):401–408. doi: 10.1046/j.1365-2567.2003.01582.x

Table 1.

Tissue vacuolization and parasite load at the site of L. major infection is reduced in NAC-treated BALB/c mice

	Vacuolated area (µm²)^‡

	7th week	10th week	Parasite load (no. parasites/field)^§ 7th week
BALB/c H₂O^†	316 016 ± 44 643	361 635 ± 31 040	1469 ± 197
BALB/c NAC^†	142 343 ± 37 242^*	198 279 ± 34 832^*	424 ± 104^*

^†

Mice were euthanized on the 7th and 10th weeks following the primary infection and their lesions were harvested for morphometric analysis. The data presented represent the mean ± SD for at least three animals in each group, at each time-point.

^‡

The values represent the means of vacuolated areas obtained through the analysis of 10 fields/lesion ± the standard deviation, using a magnification of 200 ×, covering a total area of 759 310 µm², which accounts for more than 60% of the tissue fragment area.

^§

The values represent the means parasite number obtained through the analysis of 10 fields/lesion ± the standard deviation, using a magnification of 630 ×

Statistically significant when compared to infected control mice using Student's t-test (P < 0·05) as provided by the statistical analysis software by SAS, JMP.